A randomized clinical trial of low-dose cannabis extract in Alzheimer's disease

OG article by Rafael de Morais Cury^*

Taynara da Silva*

Fernando Cezar-dos-Santos

Yasmin Rafaela Correia Fakih

Karlin Andrea Ramírez Narvaez

Murilo Chaves Gouvea

Carlos Espínola

Charles Francisco Ferreira

Wagner Antonio Chiba de Castro

Fabrício Alano Pamplona

Elton Gomes da Silva

Maíra Assunção Bicca

Francisney Pinto Nascimento

October 30 2025

26-week trial. 60-80 year olds.

Daily: THC-CBD extract or placebo.

Breakthrough:

MMSE scores rose sharply.

Cannabis beat placebo.

Safe.

No extra side effects.

Next:

Larger trials needed.

Promising therapy.