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Brain Stimulation May Reduce Cannabis Addiction in People with Multiple Sclerosis

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October 07 2025






Study Overview

A new NYU Langone Health study shows a brain stimulation device reduces cannabis use in women with multiple sclerosis (MS).The device, used at home, delivers weak electrical currents paired with mindfulness meditation.



Background

  • Over 50% of MS patients use cannabis for pain, spasms, and sleep issues.

  • Up to 20% develop cannabis use disorder, marked by heavy, disruptive use.

  • No approved treatments exist for long-term cannabis dependency.



Method

  • 47 women with MS and cannabis use disorder participated.

  • Daily 20-minute transcranial direct current stimulation (tDCS) sessions for 4 weeks.

  • tDCS targets the prefrontal cortex, aiding decision-making and emotional regulation.

  • Sessions paired with guided online mindfulness meditation via telehealth.

  • Compared active stimulation to a placebo mimicking the sensation.



Results

  • Cannabis use dropped from ~5 days/week to ~2 days/week.

  • Reduced withdrawal symptoms: anxiety, sleep issues, appetite loss, irritability.

  • First study to show tDCS benefits for MS patients with cannabis use disorder.

Published in Drug and Alcohol Dependence



How It Works

  • tDCS enhances neuroplasticity, helping the brain form new connections.

  • Mindfulness meditation may amplify effects, easing cravings.

  • Offers a safe, portable recovery tool.

"tDCS could fill a critical gap in care," says Leigh Charvet, PhD.


Next Steps

  • Nationwide study to test tDCS for cannabis use disorder without MS.

  • Expanded study to include more MS patients, both men and women.

  • Exploring how reduced cannabis use may improve MS symptoms.

For more health news, visit www.foxnews.com/health



Funding and Disclosures

  • Funded by NIH grant R21DA055427.

  • Researchers Giuseppina Pilloni and Leigh Charvet have ties to Soterix Medical, managed per NYU Langone policies.

 
 
 

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