Brain Stimulation May Reduce Cannabis Addiction in People with Multiple Sclerosis
- barneyelias0
- 1 hour ago
- 1 min read
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October 07 2025
Study Overview
A new NYU Langone Health study shows a brain stimulation device reduces cannabis use in women with multiple sclerosis (MS).The device, used at home, delivers weak electrical currents paired with mindfulness meditation.
Background
Over 50% of MS patients use cannabis for pain, spasms, and sleep issues.
Up to 20% develop cannabis use disorder, marked by heavy, disruptive use.
No approved treatments exist for long-term cannabis dependency.
Method
47 women with MS and cannabis use disorder participated.
Daily 20-minute transcranial direct current stimulation (tDCS) sessions for 4 weeks.
tDCS targets the prefrontal cortex, aiding decision-making and emotional regulation.
Sessions paired with guided online mindfulness meditation via telehealth.
Compared active stimulation to a placebo mimicking the sensation.
Results
Cannabis use dropped from ~5 days/week to ~2 days/week.
Reduced withdrawal symptoms: anxiety, sleep issues, appetite loss, irritability.
First study to show tDCS benefits for MS patients with cannabis use disorder.
Published in Drug and Alcohol Dependence
How It Works
tDCS enhances neuroplasticity, helping the brain form new connections.
Mindfulness meditation may amplify effects, easing cravings.
Offers a safe, portable recovery tool.
"tDCS could fill a critical gap in care," says Leigh Charvet, PhD.
Next Steps
Nationwide study to test tDCS for cannabis use disorder without MS.
Expanded study to include more MS patients, both men and women.
Exploring how reduced cannabis use may improve MS symptoms.
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Funding and Disclosures
Funded by NIH grant R21DA055427.
Researchers Giuseppina Pilloni and Leigh Charvet have ties to Soterix Medical, managed per NYU Langone policies.
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