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A sports drink formulation containing cannabidiol (CBD) and cannabigerol (CBG) among other ingredients may support recovery from exercise-induced delayed-onset muscle soreness (DOMS), according to a study published in the Journal of the International Society of Sports Nutrition.
The randomized, double-blind, placebo-controlled pilot study included a total of 40 participants who were randomly assigned to either the active or placebo groups. The 2 groups were well-balanced in terms of demographic and baseline characteristics.
The beverage powder contained CBD and CBG but also included branched chain amino acids (BCAAs), beta-caryophyllene (BCP), and magnesium citrate to aid in recovery similar to other commercially available products.
“Results from this pilot study revealed a good safety and tolerability profile associated with a beverage powder containing CBD, CBG, BCP, BCAAs, and magnesium citrate. Preliminary results on effects suggested that repeated-dosing of this cannabinoid-based formulation over 3.5 days improved functional aspects of recovery, and could decrease self-reported soreness or discomfort, associated with DOMS,” the authors wrote.
At 72 hours after exercise, participants in the active group reported less average soreness/discomfort compared to the placebo group (-1.33; 85% CI, -2.55 to -0.10), which the authors noted was a moderate treatment difference (as it was not significant at the 95% confidence interval).
A potential treatment effect was observed for interference in daily activities due to soreness, discomfort, or stiffness at 48 hours after exercise. Compared to placebo, the active group had a decrease of -1.82 (95% CI, -3.63 to -.01) on the rating of interference at 48 hours post-workout.
No difference was observed between the 2 groups related to objective measures of sleep quality, mood disturbance, or recovery.
One adverse event (AE; diarrhea) was reported in the active group while 2 AEs were reported in the placebo group (dry mouth and eye rash). These results indicated that the beverage was well tolerated among participants.
