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CBD May Increase Effects of THC Edibles, Study Finds

By Alexander Beadle

Published: Feb 17, 2023

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Relatively high doses of CBD in edibles may increase the intoxicating and adverse effects of THC, a new study suggests.

Published in JAMA Network Open, researchers from the University of Washington and the Johns Hopkins School of Medicine found that individuals given brownies containing high doses of CBD experienced stronger subjective effects than those given brownies made from a THC-dominant strain, despite both edibles containing the same dose of THC.

At first, this finding might appear to contradict previous work, which has suggested that CBD works as a buffer for some of THC’s acute effects. However, the researchers behind this new trial believe that this discrepancy may be down to the fact that their study used edible cannabis products, while most other research has focused on inhalable cannabis or other methods of administration.

Edibles feel stronger when they have high CBD