ER Doctors Are Sounding the Alarm on a Fast-Growing Cannabis Illness

OG article by University of Washington School of Medicine

December 11, 2025

Emergency departments report an increase in patients with abdominal pain and severe vomiting linked to long-term cannabis use, now classified as cannabis hyperemesis syndrome. This gastrointestinal condition starts within 24 hours of recent cannabis use and lasts several days, with affected individuals experiencing three to four episodes annually. The World Health Organization added diagnostic code R11.16 to the ICD-10 manual on October 1, aiding U.S. providers in tracking and billing. This update enables better monitoring of cases and supports research on prevalence and affected demographics, as noted by Beatriz Carlini, a research associate professor at the University of Washington School of Medicine. She emphasized its value in providing evidence of cannabis-related adverse events. Limited clinician awareness delays diagnosis, leading to repeated costly ER visits. Patients often deny cannabis as the cause, given its common use for nausea relief in conditions like chemotherapy or migraines, according to Dr. Chris Buresh, an emergency medicine specialist. The condition's triggers remain unclear, potentially tied to cannabis availability or higher THC potency. Treatment is challenging, with standard anti-nausea drugs ineffective; alternatives include Haldol, capsaicin cream, or hot showers for relief. Recovery is hindered by intermittent symptoms, continued use, and addiction difficulties in cessation. To further contextualize, rising legalization has increased exposure, highlighting the need for public education on risks. Research gaps persist, but the new code could drive studies into prevention strategies. Clinicians advocate for better training to identify symptoms early, reducing healthcare burdens. Overall, this syndrome underscores the importance of balanced views on cannabis benefits and harms.