Missouri cannabis growers fined for breaking the ‘immaculate conception’ rule

OG article by Rebecca Rivas

January 26, 2026

Missouri fined several cannabis growers up to $500,000 each last year for violating the "immaculate conception rule," which permits initial inventory flexibility in the first year post-commencement inspection but prohibits importing clones, seeds, or tissue cultures from out-of-state thereafter. Regulators found licensees importing popular varieties to meet demand, breaching seed-to-sale tracking laws requiring in-state growth. Penalties ranged from $20,000 to $500,000, with larger fines hitting major operators like High Profile ($500,000 at O’Fallon) and Good Day Farm/Codes facilities ($347,495 combined across four sites). The Missouri Division of Cannabis Regulation resolved violations via settlements instead of harsher actions. After the first year, growers must use seeds, request state-approved seed imports, or source clones from Missouri-licensed cultivators. Experts note starting from seed delays production (1–6 weeks) compared to easier clones, but promotes innovation. Instructor Ryan Schepers emphasized breeding focus over reliance on external trends. The state eyes potential federal guidance shifts on clones/seeds amid recent hemp restrictions, but currently enforces strict in-state sourcing to comply with federal illegality of interstate marijuana transport. This clarifies rules for ongoing compliance.