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Cannabinoids, Especially CBD With THC, Offer Effective Relief for Migraine, Study Finds

OG article by Anthony Martinelli


October 24, 2025






A study from Brazilian and U.S. researchers tested cannabinoids (CBD, CBG, low-dose THC) on migraine models in animals. CBD alone and CBD/THC or CBD/CBG combos reduced pain and light sensitivity induced by CGRP and PACAP. CBD/THC was most effective, lasting up to 3 hours and aiding chronic models for 13 days without sedation or anxiety. Findings suggest cannabinoids as safe migraine treatments.

 
 
 

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